Nesbit is an unincorporated community in the Hills Region, DeSoto County, Mississippi. Nesbit has a population of 6629 and is approximately 7 miles (11 km) south of Horn Lake, approximately 9 miles (14 km) south of Southaven and approximately 5 miles (8.0 km) north of Hernando near U.S. Route 51 and Interstate 55.
Nesbit is famous for its blues artists born and raised. Kenny Brown, blues guitarist was born (1953) and grew up in Nesbit. Mississippi Joe Callicott, blues singer and guitarist (1900-1969; was born and lived in Nesbit.